Winning Streak on the Line: Wednesday’s Best College Basketball Bets

After two straight winning nights to start the season, our college hoops betting card looks to stay hot with five intriguing Wednesday matchups.
Tarleton Texans forward Chris Mpaka (23)
Tarleton Texans forward Chris Mpaka (23) | Rick Osentoski-Imagn Images

We have moved on to Day 3 of the NCAA Basketball season. After a 3-2 start on Day 1, we went 3-2 again on Day 2.

Riding the Momentum into Day Three

Oregon’s one-point win was disappointing, and Kentucky didn’t come close to the total of 150.5. That puts us at 6-4 overall and +1.54 units on BetStamp.

This slate might not be the strongest of the week, but there’s still plenty of value to be found. Let’s dive into Wednesday’s best bets.

Southern Indiana Screaming Eagles vs. Butler Bulldogs

Trey Thomas is a name college basketball fans will want to know. The former Bethune-Cookman standout joins Southern Indiana and brings instant scoring ability. Butler struggled defensively last season and may still have issues early on. This one has potential upset vibes, but the safer play is on Southern Indiana covering the spread.

Pick: Southern Indiana +21

Predicted Score: Butler 75, Southern Indiana 70

South Dakota Coyotes vs. Creighton Bluejays

South Dakota loved to run last season, but that tempo won’t work against one of the best shooting teams in the country. The BluejaysTarl, led by newcomers Josh Dix and Owen Freeman from Iowa, shouldn’t have trouble filling the gaps left by Ryan Kalkbrenner. Expect a big win for Creighton at home.

Pick: Creighton -28.5

Predicted Score: Creighton 91, South Dakota 61

Tarleton State Texans vs. LSU Tigers

Tarleton State faced early uncertainty with Billy Gillespie’s status, but he’s back on the sideline, and his team plays with grit. The Texans will try to pressure LSU’s new-look roster, and the Tigers’ chemistry remains a question. Expect a close battle.

Pick: Tarleton State +18.5

Predicted Score: LSU 72, Tarleton State 68

North Alabama Lions vs. Mississippi State Bulldogs

Cornelious Williams will be a force inside for North Alabama, creating problems for Mississippi State’s inexperienced frontcourt. The Bulldogs need to hit shots — something they struggled with last season. This total looks inflated for these two teams.

Pick: Under 153.5

Predicted Score: Mississippi State 82, North Alabama 62

Eastern Washington Eagles vs. Loyola Marymount Lions

Eastern Washington put up a fight in its six-point loss to UCLA but struggled with turnovers. Loyola Marymount will look to exploit that by pushing the pace and forcing mistakes. With the spread in single digits, the Lions look like the right side.

Pick: Loyola Marymount -7.5

Predicted Score: Loyola Marymount 82, Eastern Washington 68

Enjoy the games! Remember, all picks are tracked on BetStamp. Let’s keep the streak rolling and make it three straight winning days to start the 2025-26 season.

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