NCAA Basketball: Top 20 biggest tournament upsets of all time

By Brock Zimmermann | Apr 19, 2017

Mar 24, 2016; Chicago, IL, USA; General view of a march madness logo during practice the day before the semifinals of the Midwest regional of the NCAA Tournament at United Center. Mandatory Credit: Dennis Wierzbicki-USA TODAY Sports /

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10. George Mason over UConn – 2006

After dethroning the defending champion North Carolina Tar Heels in the second round, the Patriots weren’t done yet. They went on to beat No. 7 seeded Wichita State in order to reach the Elite Eight, where they faced the No. 1 seeded UConn Huskies.

UConn reached as high as No. 2 in the AP Poll and entered with a record of 30-3. They took George Mason to overtime before falling to the Cinderella team. They weren’t able to slow down the magical season as a last second buzzer beater didn’t fall against the Patriots.

The Patriots reached No. 25 in the AP poll for one week but two late-season losses to Hofstra hurt the team’s resume. George Mason is one of three No. 11 seed teams to make the Final Four.

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